Plasma is replenished in the body much more quickly than blood cells. The FDA sets the guidelines and it’s based on weight – the ranges are 110-149 pounds, 150-174 pounds, and 175-400 pounds. Note that losing more than two litres of blood can be fatal. 7 ml sample of plasma, then digested them with proteases and analyzed the fragments by high-resolution liquid chromatography mass spectrometry. Other less common tests come in bottles up to 6 ml in volume and blood culture bottles are the largest size at 10 ml.
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